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Auditory Phenotype and Histopathologic Findings of a Mutant Nlrp3 Expression Mouse Model
OBJECTIVE: The pathogenesis of hearing loss in autoinflammatory disorders due to activation of the inflammasome remains incompletely understood. Previously no animals expressing mutant Nlrp3 (NOD-, LRR- and pyrin domain-containing protein 3) survived to an age when hearing evaluation was possible du...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263128/ https://www.ncbi.nlm.nih.gov/pubmed/35812087 http://dx.doi.org/10.3389/fneur.2022.890256 |