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Auditory Phenotype and Histopathologic Findings of a Mutant Nlrp3 Expression Mouse Model

OBJECTIVE: The pathogenesis of hearing loss in autoinflammatory disorders due to activation of the inflammasome remains incompletely understood. Previously no animals expressing mutant Nlrp3 (NOD-, LRR- and pyrin domain-containing protein 3) survived to an age when hearing evaluation was possible du...

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Detalles Bibliográficos
Autores principales: Kim, Yehree, Lee, Sang-Yeon, Kim, Min Young, Park, Kyusun, Han, Jin Hee, Kim, Jung Ho, Kim, Bong Jik, Choi, Byung Yoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263128/
https://www.ncbi.nlm.nih.gov/pubmed/35812087
http://dx.doi.org/10.3389/fneur.2022.890256