TGFβ reprograms TNF stimulation of macrophages towards a non-canonical pathway driving inflammatory osteoclastogenesis

It is well-established that receptor activator of NF-κB ligand (RANKL) is the inducer of physiological osteoclast differentiation. However, the specific drivers and mechanisms driving inflammatory osteoclast differentiation under pathological conditions remain obscure. This is especially true given...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Yuhan, Inoue, Kazuki, Du, Yong, Baker, Stacey J., Reddy, E. Premkumar, Greenblatt, Matthew B., Zhao, Baohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263175/
https://www.ncbi.nlm.nih.gov/pubmed/35798734
http://dx.doi.org/10.1038/s41467-022-31475-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263175/
https://www.ncbi.nlm.nih.gov/pubmed/35798734
http://dx.doi.org/10.1038/s41467-022-31475-1

Ejemplares similares