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TGFβ reprograms TNF stimulation of macrophages towards a non-canonical pathway driving inflammatory osteoclastogenesis
It is well-established that receptor activator of NF-κB ligand (RANKL) is the inducer of physiological osteoclast differentiation. However, the specific drivers and mechanisms driving inflammatory osteoclast differentiation under pathological conditions remain obscure. This is especially true given...
Autores principales: | Xia, Yuhan, Inoue, Kazuki, Du, Yong, Baker, Stacey J., Reddy, E. Premkumar, Greenblatt, Matthew B., Zhao, Baohong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263175/ https://www.ncbi.nlm.nih.gov/pubmed/35798734 http://dx.doi.org/10.1038/s41467-022-31475-1 |
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