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Upregulated miRNAs on the TP53 and RB1 Binding Seedless Regions in High-Risk HPV-Associated Penile Cancer

Cancer development by the human papillomavirus (HPV) infection can occur through the canonical HPV/p53/RB1 pathway mediated by the E2/E6/E7 viral oncoproteins. During the transformation process, HPV inserts its genetic material into host Integration Sites (IS), affecting coding genes and miRNAs. In...

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Detalles Bibliográficos
Autores principales: da Silva, Jenilson, da Costa, Carla Cutrim, de Farias Ramos, Ingryd, Laus, Ana Carolina, Sussuchi, Luciane, Reis, Rui Manuel, Khayat, André Salim, Cavalli, Luciane Regina, Pereira, Silma Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263206/
https://www.ncbi.nlm.nih.gov/pubmed/35812732
http://dx.doi.org/10.3389/fgene.2022.875939