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ACLY and CKD: A Mendelian Randomization Analysis

INTRODUCTION: Adenosine triphosphate-citrate lyase (ACLY) inhibition is a therapeutic strategy under investigation for atherosclerotic cardiovascular disease, nonalcoholic steatohepatitis, and metabolic syndrome. Mouse models suggest that ACLY inhibition could reduce inflammation and kidney fibrosis...

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Detalles Bibliográficos
Autores principales: Mohammadi-Shemirani, Pedrum, Chong, Michael, Perrot, Nicolas, Pigeyre, Marie, Steinberg, Gregory R., Paré, Guillaume, Krepinsky, Joan C., Lanktree, Matthew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263230/
https://www.ncbi.nlm.nih.gov/pubmed/35812273
http://dx.doi.org/10.1016/j.ekir.2022.04.013