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ACLY and CKD: A Mendelian Randomization Analysis
INTRODUCTION: Adenosine triphosphate-citrate lyase (ACLY) inhibition is a therapeutic strategy under investigation for atherosclerotic cardiovascular disease, nonalcoholic steatohepatitis, and metabolic syndrome. Mouse models suggest that ACLY inhibition could reduce inflammation and kidney fibrosis...
Autores principales: | Mohammadi-Shemirani, Pedrum, Chong, Michael, Perrot, Nicolas, Pigeyre, Marie, Steinberg, Gregory R., Paré, Guillaume, Krepinsky, Joan C., Lanktree, Matthew B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263230/ https://www.ncbi.nlm.nih.gov/pubmed/35812273 http://dx.doi.org/10.1016/j.ekir.2022.04.013 |
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