Abrogation of Rb Tumor Suppression Initiates GBM in Differentiated Astrocytes by Driving a Progenitor Cell Program

Glioblastoma (GBM) remains lethal with no effective treatments. Despite the comprehensive identification of commonly perturbed molecular pathways, little is known about the disease’s etiology, particularly in early stages. Several studies indicate that GBM is initiated in neural progenitor and/or st...

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Detalles Bibliográficos
Autores principales: Adhikari, Amit S., Sullivan, Teresa, Bargaje, Rhishikesh, Lu, Lucy, O’Sullivan, T Norene, Song, Yurong, Van Dyke, Terry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263358/
https://www.ncbi.nlm.nih.gov/pubmed/35814428
http://dx.doi.org/10.3389/fonc.2022.904479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263358/
https://www.ncbi.nlm.nih.gov/pubmed/35814428
http://dx.doi.org/10.3389/fonc.2022.904479

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