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TTF1 suppresses neuroblastoma growth and induces neuroblastoma differentiation by targeting TrkA and the miR-204/TrkB axis

Neuroblastoma (NB) is the most common extracranial malignant solid tumor in children. We found that TTF1, TrkA, and miR-204 were lowly expressed, whereas TrkB was highly expressed in undifferentiated NB tissues. Meanwhile, TTF1 expression correlated positively with TrkA and miR-204 expression but ne...

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Detalles Bibliográficos
Autores principales: Yang, Tianyou, Li, Jiahao, Zhuo, Zhenjian, Zeng, Huijuan, Tan, Tianbao, Miao, Lei, Zheng, Manna, Yang, Jiliang, Pan, Jing, Hu, Chao, Zou, Yan, He, Jing, Xia, Huimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263519/
https://www.ncbi.nlm.nih.gov/pubmed/35811845
http://dx.doi.org/10.1016/j.isci.2022.104655