Cargando…
TTF1 suppresses neuroblastoma growth and induces neuroblastoma differentiation by targeting TrkA and the miR-204/TrkB axis
Neuroblastoma (NB) is the most common extracranial malignant solid tumor in children. We found that TTF1, TrkA, and miR-204 were lowly expressed, whereas TrkB was highly expressed in undifferentiated NB tissues. Meanwhile, TTF1 expression correlated positively with TrkA and miR-204 expression but ne...
Autores principales: | Yang, Tianyou, Li, Jiahao, Zhuo, Zhenjian, Zeng, Huijuan, Tan, Tianbao, Miao, Lei, Zheng, Manna, Yang, Jiliang, Pan, Jing, Hu, Chao, Zou, Yan, He, Jing, Xia, Huimin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263519/ https://www.ncbi.nlm.nih.gov/pubmed/35811845 http://dx.doi.org/10.1016/j.isci.2022.104655 |
Ejemplares similares
-
NGF FLIPs TrkA onto the death TRAIL in neuroblastoma cells
por: Ruggeri, P, et al.
Publicado: (2016) -
TrkA Co-Receptors: The Janus Face of TrkA?
por: Trouvilliez, Sarah, et al.
Publicado: (2023) -
Identification of novel candidate compounds targeting TrkB to induce apoptosis in neuroblastoma
por: Nakamura, Yohko, et al.
Publicado: (2014) -
NGF sensitizes TrkA SH-SY5Y neuroblastoma cells to TRAIL-induced apoptosis
por: Ruggeri, P, et al.
Publicado: (2016) -
A quest for the stereo-electronic requirements for selective agonism for the neurotrophin receptors TrkA and TrkB in 17-spirocyclic-dehydroepiandrosterone derivatives
por: Narducci, Daniele, et al.
Publicado: (2023)