Epithelial HNF4A shapes the intraepithelial lymphocyte compartment via direct regulation of immune signaling molecules

Hepatocyte nuclear factor 4 α (HNF4A) is a highly conserved nuclear receptor that has been associated with ulcerative colitis. In mice, HNF4A is indispensable for the maintenance of intestinal homeostasis, yet the underlying mechanisms are poorly characterized. Here, we demonstrate that the expressi...

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Detalles Bibliográficos
Autores principales: Lei, Xuqiu, Ketelut-Carneiro, Natalia, Shmuel-Galia, Liraz, Xu, Weili, Wilson, Ruth, Vierbuchen, Tim, Chen, Yongzhi, Reboldi, Andrea, Kang, Joonsoo, Edelblum, Karen L., Ward, Doyle, Fitzgerald, Katherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263552/
https://www.ncbi.nlm.nih.gov/pubmed/35792863
http://dx.doi.org/10.1084/jem.20212563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263552/
https://www.ncbi.nlm.nih.gov/pubmed/35792863
http://dx.doi.org/10.1084/jem.20212563

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