Pharmacological Responses of the G542X-CFTR to CFTR Modulators

Cystic fibrosis (CF) is a lethal hereditary disease caused by loss-of-function mutations of the chloride channel cystic fibrosis transmembrane conductance regulator (CFTR). With the development of small-molecule CFTR modulators, including correctors that facilitate protein folding and expression and...

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Detalles Bibliográficos
Autores principales: Fang, Xinxiu, Yeh, Jiunn-Tyng, Hwang, Tzyh-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263564/
https://www.ncbi.nlm.nih.gov/pubmed/35813815
http://dx.doi.org/10.3389/fmolb.2022.921680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263564/
https://www.ncbi.nlm.nih.gov/pubmed/35813815
http://dx.doi.org/10.3389/fmolb.2022.921680

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