miR-155 down-regulation protects the heart from hypoxic damage by activating fructose metabolism in cardiac fibroblasts

INTRODUCTION: Hypoxia-inducible factor (HIF)1α has been shown to be activated and induces a glycolytic shift under hypoxic condition, however, little attention was paid to the role of HIF1α-actuated fructolysis in hypoxia-induced heart injury. OBJECTIVES: In this study, we aim to explore the molecul...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yu, Zhang, Hong, Yang, Zhan, Zhang, Xin-hua, Miao, Qing, Li, Min, Zhai, Tian-ying, Zheng, Bin, Wen, Jin-kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263644/
https://www.ncbi.nlm.nih.gov/pubmed/35777901
http://dx.doi.org/10.1016/j.jare.2021.10.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263644/
https://www.ncbi.nlm.nih.gov/pubmed/35777901
http://dx.doi.org/10.1016/j.jare.2021.10.007

Ejemplares similares