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miR-155 down-regulation protects the heart from hypoxic damage by activating fructose metabolism in cardiac fibroblasts
INTRODUCTION: Hypoxia-inducible factor (HIF)1α has been shown to be activated and induces a glycolytic shift under hypoxic condition, however, little attention was paid to the role of HIF1α-actuated fructolysis in hypoxia-induced heart injury. OBJECTIVES: In this study, we aim to explore the molecul...
Autores principales: | Zhang, Yu, Zhang, Hong, Yang, Zhan, Zhang, Xin-hua, Miao, Qing, Li, Min, Zhai, Tian-ying, Zheng, Bin, Wen, Jin-kun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263644/ https://www.ncbi.nlm.nih.gov/pubmed/35777901 http://dx.doi.org/10.1016/j.jare.2021.10.007 |
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