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Upregulation of FOXO1 contributes to lipopolysaccharide-induced pulmonary endothelial injury by induction of autophagy

BACKGROUND: Autophagy is activated during the pathogenesis of endothelial dysfunction and sepsis-associated acute lung injury (ALI). This study aimed to investigate whether autophagy affected endothelial barrier dysfunction and lung injury in a murine model of lipopolysaccharide (LPS)-induced ALI, a...

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Detalles Bibliográficos
Autores principales: Zhao, Ying, Zhang, Hui, Zhang, Shu-Li, Wei, Juan, Zheng, Liang-Liang, Du, Jian-Kui, Zhu, Xiao-Yan, Jiang, Lai, Liu, Yu-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263762/
https://www.ncbi.nlm.nih.gov/pubmed/35813334
http://dx.doi.org/10.21037/atm-21-5380