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Benchmarking of 5 algorithms for high-resolution genotyping of human leukocyte antigen class I genes from blood and tissue samples

BACKGROUND: Specific alterations in human leukocyte antigen class I (HLA-I) loci are associated with clinical outcomes for immune checkpoint inhibitors, which increase the clinical relevance of accurate high-resolution HLA genotyping in immuno-oncology applications. Numerous algorithms have been dev...

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Detalles Bibliográficos
Autores principales: Xin, Hua, Li, Jiurong, Sun, Hongbin, Zhao, Nan, Yao, Bing, Zhong, Wenwen, Ma, Bo, Wang, Dejuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263794/
https://www.ncbi.nlm.nih.gov/pubmed/35813337
http://dx.doi.org/10.21037/atm-22-875