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Mycobacterium tuberculosis Methyltransferase Rv1515c Can Suppress Host Defense Mechanisms by Modulating Immune Functions Utilizing a Multipronged Mechanism

Mycobacterium tuberculosis (M. tb) gene Rv1515c encodes a conserved hypothetical protein exclusively present within organisms of MTB complex and absent in non-pathogenic mycobacteria. In silico analysis revealed that Rv1515c contain S-adenosylmethionine binding site and methyltransferase domain. The...

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Detalles Bibliográficos
Autores principales: Rani, Anshu, Alam, Anwar, Ahmad, Faraz, P., Manjunath, Saurabh, Abhinav, Zarin, Sheeba, Mitra, Dipendra Kumar, Hasnain, Seyed E., Ehtesham, Nasreen Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9263924/
https://www.ncbi.nlm.nih.gov/pubmed/35813825
http://dx.doi.org/10.3389/fmolb.2022.906387