Serum protein level as a predictor of therapeutic response and adverse effects associated with afatinib use

BACKGROUND: Afatinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor with significant serum protein binding. Total protein level was found to be associated with plasma afatinib level. The trough serum concentration was shown to be associated with development of adverse effect...

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Detalles Bibliográficos
Autores principales: Kwok, Wang Chun, Ho, James Chung Man, Tam, Terence Chi Chun, Ip, Mary Sau Man, Lam, David Chi Leung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264096/
https://www.ncbi.nlm.nih.gov/pubmed/35813726
http://dx.doi.org/10.21037/jtd-21-1649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264096/
https://www.ncbi.nlm.nih.gov/pubmed/35813726
http://dx.doi.org/10.21037/jtd-21-1649

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