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Serum protein level as a predictor of therapeutic response and adverse effects associated with afatinib use
BACKGROUND: Afatinib is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor with significant serum protein binding. Total protein level was found to be associated with plasma afatinib level. The trough serum concentration was shown to be associated with development of adverse effect...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
AME Publishing Company
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264096/ https://www.ncbi.nlm.nih.gov/pubmed/35813726 http://dx.doi.org/10.21037/jtd-21-1649 |