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Effect of Surface Interactions on Microsphere Loading in Dissolving Microneedle Patches

[Image: see text] Microneedle (MN) patches enable simple self-administration of drugs via the skin. In this study, we sought to deliver drug-loaded microspheres (MSs) using MN patches and found that the poly(lactic-co-glycolic acid) (PLGA) MSs failed to localize in the MN tips during fabrication, th...

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Detalles Bibliográficos
Autores principales: Jang, Derek, Tang, Jie, Schwendeman, Steven P., Prausnitz, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264316/
https://www.ncbi.nlm.nih.gov/pubmed/35732055
http://dx.doi.org/10.1021/acsami.2c05795