Nucleic Acid-Loaded Lipid Nanoparticle Interactions with Model Endosomal Membranes

[Image: see text] Lipid nanoparticles (LNPs) are important delivery systems for RNA-based therapeutics, yet the mechanism of their interaction with endosomal membranes remains unclear. Here, the interactions of nucleic acid-loaded LNPs that contain an ionizable lipid with models of the early and lat...

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Detalles Bibliográficos
Autores principales: Spadea, Alice, Jackman, Mark, Cui, Lili, Pereira, Sara, Lawrence, M. Jayne, Campbell, Richard A., Ashford, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264317/
https://www.ncbi.nlm.nih.gov/pubmed/35758331
http://dx.doi.org/10.1021/acsami.2c06065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264317/
https://www.ncbi.nlm.nih.gov/pubmed/35758331
http://dx.doi.org/10.1021/acsami.2c06065

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