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Nucleic Acid-Loaded Lipid Nanoparticle Interactions with Model Endosomal Membranes
[Image: see text] Lipid nanoparticles (LNPs) are important delivery systems for RNA-based therapeutics, yet the mechanism of their interaction with endosomal membranes remains unclear. Here, the interactions of nucleic acid-loaded LNPs that contain an ionizable lipid with models of the early and lat...
Autores principales: | Spadea, Alice, Jackman, Mark, Cui, Lili, Pereira, Sara, Lawrence, M. Jayne, Campbell, Richard A., Ashford, Marianne |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264317/ https://www.ncbi.nlm.nih.gov/pubmed/35758331 http://dx.doi.org/10.1021/acsami.2c06065 |
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