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Huntington’s disease iPSC models—using human patient cells to understand the pathology caused by expanded CAG repeats

A major advance in the study of Huntington’s disease (HD) has been the development of human disease models employing induced pluripotent stem cells (iPSCs) derived from patients with HD. Because iPSCs provide an unlimited source of cells and can be obtained from large numbers of HD patients, they ar...

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Detalles Bibliográficos
Autores principales: Kaye, Julia, Reisine, Terry, Finkbeiner, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty Opinions Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264339/
https://www.ncbi.nlm.nih.gov/pubmed/35865413
http://dx.doi.org/10.12703/r/11-16