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Whole genome sequencing–based copy number variations reveal novel pathways and targets in Alzheimer's disease

INTRODUCTION: A few copy number variations (CNVs) have been reported for Alzheimer's disease (AD). However, there is a lack of a systematic investigation of CNVs in AD based on whole genome sequencing (WGS) data. METHODS: We used four methods to identify consensus CNVs from the WGS data of 1,41...

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Detalles Bibliográficos
Autores principales: Ming, Chen, Wang, Minghui, Wang, Qian, Neff, Ryan, Wang, Erming, Shen, Qi, Reddy, Joseph S., Wang, Xue, Allen, Mariet, Ertekin‐Taner, Nilüfer, De Jager, Philip L., Bennett, David A., Haroutunian, Vahram, Schadt, Eric, Zhang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264340/
https://www.ncbi.nlm.nih.gov/pubmed/34918867
http://dx.doi.org/10.1002/alz.12507