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Specific Peptide from the Novel W-Tau Isoform Inhibits Tau and Amyloid β Peptide Aggregation In Vitro

[Image: see text] W-Tau, a new tau human-specific splicing isoform generated by intron retention, has been recently described. This isoform contains an 18-residue unique sequence corresponding to the translation of the retained region of intron 12. In this work, we have described that such 18-amino-...

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Detalles Bibliográficos
Autores principales: Cuadros, Raquel, Pérez, Mar, Ruiz-Gabarre, Daniel, Hernández, Félix, García-Escudero, Vega, Avila, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264359/
https://www.ncbi.nlm.nih.gov/pubmed/35695727
http://dx.doi.org/10.1021/acschemneuro.2c00188