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Toward Rapid Aspartic Acid Isomer Localization in Therapeutic Peptides Using Cyclic Ion Mobility Mass Spectrometry

[Image: see text] There is an increasing emphasis on the critical evaluation of interbatch purity and physical stability of therapeutic peptides. This is due to concerns over the impact that product- and process-related impurities may have on safety and efficacy of this class of drug. Aspartic acid...

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Detalles Bibliográficos
Autores principales: Gibson, Katherine, Cooper-Shepherd, Dale A., Pallister, Edward, Inman, Sophie E., Jackson, Sophie E., Lindo, Viv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264384/
https://www.ncbi.nlm.nih.gov/pubmed/35609180
http://dx.doi.org/10.1021/jasms.2c00053