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Potentiation of endocannabinoids and other lipid amides prevents hyperalgesia and inflammation in a pre-clinical model of migraine

Targeting fatty acid amide hydrolase (FAAH) is a promising therapeutic strategy to combat certain forms of pain, including migraine headache. FAAH inhibitors, such as the O-biphenyl-3-yl carbamate URB597, have been shown to produce anti-hyperalgesic effects in animal models of migraine. The objectiv...

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Detalles Bibliográficos
Autores principales: Greco, Rosaria, Demartini, Chiara, Zanaboni, Anna Maria, Francavilla, Miriam, Reggiani, Angelo, Realini, Natalia, Scarpelli, Rita, Piomelli, Daniele, Tassorelli, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264488/
https://www.ncbi.nlm.nih.gov/pubmed/35799128
http://dx.doi.org/10.1186/s10194-022-01449-1