Efficacy of donepezil for the treatment of oxaliplatin-induced peripheral neuropathy: DONEPEZOX, a protocol of a proof of concept, randomised, triple-blinded and multicentre trial

BACKGROUND: The use of oxaliplatin in digestive tract cancers could induce severe peripheral neuropathy (OIPN) decreasing the quality of life of patients and survivors. There is currently, no univocal treatment for these peripheral neuropathies. Donepezil, a reversible inhibitor of cholinesterase, u...

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Detalles Bibliográficos
Autores principales: Kerckhove, Nicolas, Tougeron, David, Lepage, Côme, Pezet, Denis, Le Malicot, Karine, Pelkowski, Manon, Pereira, Bruno, Balayssac, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264497/
https://www.ncbi.nlm.nih.gov/pubmed/35799138
http://dx.doi.org/10.1186/s12885-022-09806-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264497/
https://www.ncbi.nlm.nih.gov/pubmed/35799138
http://dx.doi.org/10.1186/s12885-022-09806-8

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