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KAP1 phosphorylation promotes the survival of neural stem cells after ischemia/reperfusion by maintaining the stability of PCNA

AIMS: To explore the function of phosphorylation of KAP1 (p-KAP1) at the serine-824 site (S824) in the proliferation and apoptosis of endogenous neural stem cells (NSCs) after cerebral ischemic/reperfusion (I/R). METHODS: The apoptosis and proliferation of C17.2 cells transfected with the p-KAP1-exp...

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Detalles Bibliográficos
Autores principales: Wang, Wan, Yan, Tianqing, Guo, Xinjian, Cai, Heng, Liang, Chang, Huang, Linyan, Wang, Yanling, Ma, Ping, Qi, Suhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264526/
https://www.ncbi.nlm.nih.gov/pubmed/35799276
http://dx.doi.org/10.1186/s13287-022-02962-5