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The role of LCN2 and LCN2-MMP9 in spondylitis radiographic development: gender and HLA-B27 status differences

BACKGROUND: Male HLA-B27-positive radiographic-axial spondyloarthritis (r-axSpA) patients are prone to have severe spinal radiographic progression, but the underlying mechanisms are unclear. We recently showed that persistently elevated Lipocalin 2 (LCN2; L) reflects sacroiliac joint (SIJ) inflammat...

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Detalles Bibliográficos
Autores principales: Tsui, Florence W. L., Lin, Aifeng, Sari, Ismail, Zhang, Zhenbo, Pritzker, Kenneth P. H., Tsui, Hing Wo, Inman, Robert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264538/
https://www.ncbi.nlm.nih.gov/pubmed/35804445
http://dx.doi.org/10.1186/s13075-022-02854-2