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Cyclic-di-GMP stimulates keratinocyte innate immune responses and attenuates methicillin-resistant Staphylococcus aureus colonization in a murine skin wound infection model

BACKGROUND: Staphylococcus aureus is a leading cause for morbidity and mortality associated with skin and burn wound infections. Therapeutic options for methicillin-resistant S. aureus (MRSA) have dwindled and therefore alternative treatments are urgently needed. In this study, the immuno-stimulatin...

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Detalles Bibliográficos
Autores principales: Gao, Shuai, Khan, Abidullah, Chen, Xuhong, Xiao, Guohui, van der Veen, Stijn, Chen, Yin, Lin, Xu’ai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264594/
https://www.ncbi.nlm.nih.gov/pubmed/35804301
http://dx.doi.org/10.1186/s12866-022-02583-1