Cargando…
Chidamide and venetoclax synergistically exert cytotoxicity on multiple myeloma by upregulating BIM expression
BACKGROUND: Multiple myeloma (MM) is the second most common hematologic malignancy with almost all patients eventually having relapse or refractory MM (RRMM), thus novel drugs or combination therapies are needed for improved prognosis. Chidamide and venetoclax, which target histone deacetylase and B...
Autores principales: | , , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264603/ https://www.ncbi.nlm.nih.gov/pubmed/35799216 http://dx.doi.org/10.1186/s13148-022-01306-7 |