Toward a base-resolution panorama of the in vivo impact of cytosine methylation on transcription factor binding

BACKGROUND: While methylation of CpG dinucleotides is traditionally considered antagonistic to the DNA-binding activity of most transcription factors (TFs), recent in vitro studies have revealed a more complex picture, suggesting that over a third of TFs may preferentially bind to methylated sequenc...

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Detalles Bibliográficos
Autores principales: Hernandez-Corchado, Aldo, Najafabadi, Hamed S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264634/
https://www.ncbi.nlm.nih.gov/pubmed/35799193
http://dx.doi.org/10.1186/s13059-022-02713-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264634/
https://www.ncbi.nlm.nih.gov/pubmed/35799193
http://dx.doi.org/10.1186/s13059-022-02713-y

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