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Toward a base-resolution panorama of the in vivo impact of cytosine methylation on transcription factor binding
BACKGROUND: While methylation of CpG dinucleotides is traditionally considered antagonistic to the DNA-binding activity of most transcription factors (TFs), recent in vitro studies have revealed a more complex picture, suggesting that over a third of TFs may preferentially bind to methylated sequenc...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264634/ https://www.ncbi.nlm.nih.gov/pubmed/35799193 http://dx.doi.org/10.1186/s13059-022-02713-y |