First-in-human phase I study of CLL-1 CAR-T cells in adults with relapsed/refractory acute myeloid leukemia

Relapsed or refractory (R/R) acute myeloid leukemia (AML) has a poor prognosis. In this study, we evaluated chimeric antigen receptor (CAR) T cell therapy targeting CLL-1 in adults with R/R AML patients. Patients received conditioning chemotherapy with cyclophosphamide (500 mg/m(2)) and fludarabine...

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Detalles Bibliográficos
Autores principales: Jin, Xin, Zhang, Meng, Sun, Rui, Lyu, Hairong, Xiao, Xia, Zhang, Xiaomei, Li, Fan, Xie, Danni, Xiong, Xia, Wang, Jiaxi, Lu, Wenyi, Zhang, Hongkai, Zhao, Mingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264641/
https://www.ncbi.nlm.nih.gov/pubmed/35799191
http://dx.doi.org/10.1186/s13045-022-01308-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264641/
https://www.ncbi.nlm.nih.gov/pubmed/35799191
http://dx.doi.org/10.1186/s13045-022-01308-1

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