Umbilical Cord Blood as a Source of Less Differentiated T Cells to Produce CD123 CAR-T Cells

SIMPLE SUMMARY: We used fresh or thawed Umbilical Cord Blood (UCB) to produce CAR-T cells directed against CD123, and we compared their functionality to Peripheral Blood (PB) CAR-T cells. T cells expressing CD123 CAR, derived from UCB, was exhibited through a high transduction rate, activation statu...

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Detalles Bibliográficos
Autores principales: Caël, Blandine, Galaine, Jeanne, Bardey, Isabelle, Marton, Chrystel, Fredon, Maxime, Biichle, Sabeha, Poussard, Margaux, Godet, Yann, Angelot-Delettre, Fanny, Barisien, Christophe, Bésiers, Christophe, Adotevi, Olivier, Pouthier, Fabienne, Garnache-Ottou, Francine, Bôle-Richard, Elodie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264759/
https://www.ncbi.nlm.nih.gov/pubmed/35804941
http://dx.doi.org/10.3390/cancers14133168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264759/
https://www.ncbi.nlm.nih.gov/pubmed/35804941
http://dx.doi.org/10.3390/cancers14133168

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