Iron Chelator VLX600 Inhibits Mitochondrial Respiration and Promotes Sensitization of Neuroblastoma Cells in Nutrition-Restricted Conditions

SIMPLE SUMMARY: MYC proteins are essential regulators which could affect more than 15% of all genes through an interaction with other transcription factors. High-risk neuroblastoma associated with treatment failure is characterized by amplification of the MYCN proto-oncogene. Here, we show for the f...

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Detalles Bibliográficos
Autores principales: Jakobsson, Amanda Westergren, Kundu, Snehangshu, Guo, Jing, Chowdhury, Azazul, Zhao, Miao, Lindell, Emma, Bergsten, Peter, Swartling, Fredrik J., Sjöblom, Tobias, Zhang, Xiaonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264775/
https://www.ncbi.nlm.nih.gov/pubmed/35805002
http://dx.doi.org/10.3390/cancers14133225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264775/
https://www.ncbi.nlm.nih.gov/pubmed/35805002
http://dx.doi.org/10.3390/cancers14133225

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