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Iron Chelator VLX600 Inhibits Mitochondrial Respiration and Promotes Sensitization of Neuroblastoma Cells in Nutrition-Restricted Conditions
SIMPLE SUMMARY: MYC proteins are essential regulators which could affect more than 15% of all genes through an interaction with other transcription factors. High-risk neuroblastoma associated with treatment failure is characterized by amplification of the MYCN proto-oncogene. Here, we show for the f...
Autores principales: | Jakobsson, Amanda Westergren, Kundu, Snehangshu, Guo, Jing, Chowdhury, Azazul, Zhao, Miao, Lindell, Emma, Bergsten, Peter, Swartling, Fredrik J., Sjöblom, Tobias, Zhang, Xiaonan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264775/ https://www.ncbi.nlm.nih.gov/pubmed/35805002 http://dx.doi.org/10.3390/cancers14133225 |
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