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Generation of the Chondroprotective Proteomes by Activating PI3K and TNFα Signaling

SIMPLE SUMMARY: Chondrosarcoma and inflammatory arthritis are two joint-damaging diseases. Here, we examined whether a counterintuitive approach of activating tumorigenic and inflammatory signaling may generate joint-protective proteomes in mesenchymal stem cells and chondrocytes for the treatment o...

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Detalles Bibliográficos
Autores principales: Sun, Xun, Li, Ke-Xin, Figueiredo, Marxa L., Lin, Chien-Chi, Li, Bai-Yan, Yokota, Hiroki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264838/
https://www.ncbi.nlm.nih.gov/pubmed/35804814
http://dx.doi.org/10.3390/cancers14133039