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WNT/β-Catenin-Mediated Resistance to Glucose Deprivation in Glioblastoma Stem-like Cells

SIMPLE SUMMARY: The malignant growth and therapy resistance of isocitrate dehydrogenase (IDH)-wildtype glioblastoma is thought to be driven by a subpopulation of tumor cells with cancer stem-like cell (CSC) properties. Employing a high-throughput in vitro drug screen, we identified LGK974 and berber...

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Detalles Bibliográficos
Autores principales: Yusuf, Suad, Aretz, Philippe, Nickel, Ann-Christin, Westhoff, Philipp, Sharma, Amit, Qin, Nan, Remke, Marc, Steiger, Hans-Jakob, Hänggi, Daniel, Liu, Hongjia, Liu, Hongde, Neumann, Silke, Reifenberger, Guido, Maciaczyk, Jarek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264876/
https://www.ncbi.nlm.nih.gov/pubmed/35804936
http://dx.doi.org/10.3390/cancers14133165