Quantitative Analysis of the MGMT Methylation Status of Glioblastomas in Light of the 2021 WHO Classification

SIMPLE SUMMARY: The status of a DNA repair protein called MGMT is a prognostic marker in patients with glioblastomas, the most frequent malignant brain tumor. Epigenetic silencing of this gene predicts increased sensitivity to chemotherapy. Silencing is assessed by analyzing modifications, so-called...

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Detalles Bibliográficos
Autores principales: Häni, Levin, Kopcic, Monika, Branca, Mattia, Schütz, Alessa, Murek, Michael, Söll, Nicole, Vassella, Erik, Raabe, Andreas, Hewer, Ekkehard, Schucht, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264886/
https://www.ncbi.nlm.nih.gov/pubmed/35804921
http://dx.doi.org/10.3390/cancers14133149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264886/
https://www.ncbi.nlm.nih.gov/pubmed/35804921
http://dx.doi.org/10.3390/cancers14133149

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