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Targeting Wnt/β-Catenin Signaling by TET1/FOXO4 Inhibits Metastatic Spreading and Self-Renewal of Cancer Stem Cells in Gastric Cancer

SIMPLE SUMMARY: Metastasis is the main cause of death for patients suffering gastric cancer. Epithelial-mesenchymal transition (EMT) and cancer stem cells (CSC) are critical attributes of metastasis, both of which are regulated tightly by DNA methylation and Wnt/β-catenin signaling. In this study, w...

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Detalles Bibliográficos
Autores principales: Qi, Jingjing, Cui, Di, Wu, Qi-Nian, Zhao, Qi, Chen, Zhan-Hong, Li, Lianjie, Birchmeier, Walter, Yu, Yong, Tao, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264907/
https://www.ncbi.nlm.nih.gov/pubmed/35805009
http://dx.doi.org/10.3390/cancers14133232