Endogenous Pancreatic Cancer Cell PD-1 Activates MET and Induces Epithelial-Mesenchymal Transition to Promote Cancer Progression

SIMPLE SUMMARY: Here, we describe a previously unreported mechanism of PD-1/MET interaction and PD-1 induction of epithelial-to-mesenchymal transition (EMT), which is observed early in pancreatic cancer development and progression. This oncogenic mechanism is distinct from established immune functio...

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Detalles Bibliográficos
Autores principales: Harper, Megan M., Lin, Miranda, Qasem, Shadi A., Patel, Reema A., Cavnar, Michael J., Pandalai, Prakash K., Gao, Mei, Kim, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264908/
https://www.ncbi.nlm.nih.gov/pubmed/35804822
http://dx.doi.org/10.3390/cancers14133051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264908/
https://www.ncbi.nlm.nih.gov/pubmed/35804822
http://dx.doi.org/10.3390/cancers14133051

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