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The CBP/β-Catenin Antagonist, ICG-001, Inhibits Tumor Metastasis via Blocking of the miR-134/ITGB1 Axis-Mediated Cell Adhesion in Nasopharyngeal Carcinoma

SIMPLE SUMMARY: Metastatic nasopharyngeal carcinoma (NPC) is incurable and remains the main cause of NPC death. Our previous studies found that the CBP/β-catenin Wnt antagonist, IGC-001, could inhibit the primary tumor formation of NPC tumor cells. Here, we further explored the anti-metastatic activ...

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Detalles Bibliográficos
Autores principales: Chen, Luo, Chiang, Yiu Chun, Chan, Lai Sheung, Chau, Wai Yin, Lung, Maria Li, Kahn, Michael, Lo, Kwok Wai, Mak, Nai Ki, Lung, Hong Lok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264930/
https://www.ncbi.nlm.nih.gov/pubmed/35804897
http://dx.doi.org/10.3390/cancers14133125