GNAQ and GNA11 Genes: A Comprehensive Review on Oncogenesis, Prognosis and Therapeutic Opportunities in Uveal Melanoma

SIMPLE SUMMARY: The development of uveal melanoma is a multifactorial and multi-step process, in which specific and recurrent mutations arise early. Among the recurrently mutated genes, GNAQ and GNA11 are involved in the process of carcinogenesis and are mutated in 80–90% of these tumours. Historica...

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Detalles Bibliográficos
Autores principales: Silva-Rodríguez, Paula, Fernández-Díaz, Daniel, Bande, Manuel, Pardo, María, Loidi, Lourdes, Blanco-Teijeiro, María José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264989/
https://www.ncbi.nlm.nih.gov/pubmed/35804836
http://dx.doi.org/10.3390/cancers14133066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264989/
https://www.ncbi.nlm.nih.gov/pubmed/35804836
http://dx.doi.org/10.3390/cancers14133066

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