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Combined Inhibition of FOSL-1 and YAP Using siRNA-Lipoplexes Reduces the Growth of Pancreatic Tumor

SIMPLE SUMMARY: Intercepting the molecular mechanisms implicated in pancreatic cancer progression can be an efficient therapeutic approach to treat this aggressive tumor. The Hippo pathway is a key mechanism driving tumor progression, even in the absence of KRAS activation. When this pathway is swit...

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Detalles Bibliográficos
Autores principales: Diego-González, Lara, Fernández-Carrera, Andrea, Igea, Ana, Martínez-Pérez, Amparo, Real Oliveira, M. Elisabete C. D., Gomes, Andreia C., Guerra, Carmen, Barbacid, Mariano, González-Fernández, África, Simón-Vázquez, Rosana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265026/
https://www.ncbi.nlm.nih.gov/pubmed/35804874
http://dx.doi.org/10.3390/cancers14133102