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Screening a Targeted Panel of Genes by Next-Generation Sequencing Improves Risk Stratification in Real World Patients with Acute Myeloid Leukemia

SIMPLE SUMMARY: In this study, we prospectively analyzed a cohort of 268 newly diagnosed AML patients with the objective of assessing the clinical value of screening a targeted gene panel by next-generation sequencing (NGS). We found that access to NGS data refined risk assessment for 62 patients, c...

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Detalles Bibliográficos
Autores principales: Matos, Sónia, Bernardo, Paulo, Esteves, Susana, Botelho de Sousa, Aida, Lemos, Marcos, Ribeiro, Patrícia, Silva, Madalena, Nunes, Albertina, Lobato, Joana, Frade, Maria de Jesus, da Silva, Maria Gomes, Chacim, Sérgio, Mariz, José, Esteves, Graça, Raposo, João, Espadana, Ana, Carda, José, Barbosa, Pedro, Martins, Vânia, Carmo-Fonseca, Maria, Desterro, Joana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265035/
https://www.ncbi.nlm.nih.gov/pubmed/35805006
http://dx.doi.org/10.3390/cancers14133236