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Second Generation Small Molecule Inhibitors of Gankyrin for the Treatment of Pediatric Liver Cancer

SIMPLE SUMMARY: New therapy options are needed for children with liver cancer. The goal of this study was to evaluate the role of three new compounds in the treatment of liver cancer cells. These compounds all inhibit a protein called Gankyrin, which is known to promote liver cancer by destroying tu...

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Detalles Bibliográficos
Autores principales: D’Souza, Amber M., Gnanamony, Manu, Thomas, Maria, Hanley, Peter, Kanabar, Dipti, de Alarcon, Pedro, Muth, Aaron, Timchenko, Nikolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265042/
https://www.ncbi.nlm.nih.gov/pubmed/35804840
http://dx.doi.org/10.3390/cancers14133068