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HIF-1α Inhibition Improves Anti-Tumor Immunity and Promotes the Efficacy of Stereotactic Ablative Radiotherapy (SABR)

SIMPLE SUMMARY: Stereotactic ablative radiotherapy (SABR), which irradiates tumors with high-dose radiation per fraction, promotes anti-tumor immunity by stimulating various immune processes. SABR also induces vascular damage and obstructs blood flow, thereby increasing tumor hypoxia and upregulatio...

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Detalles Bibliográficos
Autores principales: Song, Chang W., Kim, Hyunkyung, Cho, Haeun, Kim, Mi-Sook, Paek, Sun-Ha, Park, Heon-Joo, Griffin, Robert J., Terezakis, Stephanie, Cho, Lawrence Chinsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265101/
https://www.ncbi.nlm.nih.gov/pubmed/35805044
http://dx.doi.org/10.3390/cancers14133273