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Receptor tyrosine kinase MET ligand-interaction classified via machine learning from single-particle tracking data

Internalin B–mediated activation of the membrane-bound receptor tyrosine kinase MET is accompanied by a change in receptor mobility. Conversely, it should be possible to infer from receptor mobility whether a cell has been treated with internalin B. Here, we propose a method based on hidden Markov m...

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Detalles Bibliográficos
Autores principales: Malkusch, Sebastian, Rahm, Johanna V., Dietz, Marina S., Heilemann, Mike, Sibarita, Jean-Baptiste, Lötsch, Jörn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265154/
https://www.ncbi.nlm.nih.gov/pubmed/35171646
http://dx.doi.org/10.1091/mbc.E21-10-0496