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Cell Painting predicts impact of lung cancer variants

Most variants in most genes across most organisms have an unknown impact on the function of the corresponding gene. This gap in knowledge is especially acute in cancer, where clinical sequencing of tumors now routinely reveals patient-specific variants whose functional impact on the corresponding ge...

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Detalles Bibliográficos
Autores principales: Caicedo, Juan C., Arevalo, John, Piccioni, Federica, Bray, Mark-Anthony, Hartland, Cathy L., Wu, Xiaoyun, Brooks, Angela N., Berger, Alice H., Boehm, Jesse S., Carpenter, Anne E., Singh, Shantanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9265158/
https://www.ncbi.nlm.nih.gov/pubmed/35353015
http://dx.doi.org/10.1091/mbc.E21-11-0538